Coronary artery disease and factor VII hyperactivity in elderly Japanese

Kazuomi Kario; Takefumi Matsuo

doi:10.1016/0002-9149(92)90511-V

Coronary artery disease and factor VII hyperactivity in elderly Japanese

Kazuomi Kario, Takefumi Matsuo

Research output: Contribution to journal › Article › peer-review

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Abstract

High levels of factor VII (FVII) coagulant activity (FVIIc) have been associated with an increased risk of coronary artery disease and cardiac death, and are thought to be of greater significance than cholesterol in the first 5 years after screening.¹ These studies have mainly been performed in Western countries and the subjects were generally adults aged <65 years. Japan is one of the countries where the incidence of coronary artery disease is low,² and we have recently reported on FVII hyperactivity in the elderly Japanese.³ This time, to study the relation between coronary artery disease and FVII in elderly Japanese persons, we performed electrocardiography and measured FVIIc and FVII antigen (FVIIag) levels as well as blood lipid fractions.

Original language	English
Pages (from-to)	807-809
Number of pages	3
Journal	American Journal of Cardiology
Volume	69
Issue number	8
DOIs	https://doi.org/10.1016/0002-9149(92)90511-V
State	Published - 15 Mar 1992
Externally published	Yes

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title = "Coronary artery disease and factor VII hyperactivity in elderly Japanese",

abstract = "High levels of factor VII (FVII) coagulant activity (FVIIc) have been associated with an increased risk of coronary artery disease and cardiac death, and are thought to be of greater significance than cholesterol in the first 5 years after screening.1 These studies have mainly been performed in Western countries and the subjects were generally adults aged <65 years. Japan is one of the countries where the incidence of coronary artery disease is low,2 and we have recently reported on FVII hyperactivity in the elderly Japanese.3 This time, to study the relation between coronary artery disease and FVII in elderly Japanese persons, we performed electrocardiography and measured FVIIc and FVII antigen (FVIIag) levels as well as blood lipid fractions.",

author = "Kazuomi Kario and Takefumi Matsuo",

note = "Funding Information: From the Department of Internal Medicine, Hyogo Prefectural Awaji Hospital and Awaji-Hokutan Public Clinic, Hyogo, Japan. This study was supported in part by a grant from the Foundation for the Development of the Community, Tochigi, Japan. Dr. Kario{\textquoteright}s addressi s: 480-2, Ikuha, Hokutan-chyo, Tsuna-gun, Hyogo-ken, 656-16, Japan. Manuscript received September 9, 1991; revised manuscript received and accepted November 14, 1991 .",

year = "1992",

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doi = "10.1016/0002-9149(92)90511-V",

language = "English",

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journal = "American Journal of Cardiology",

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T1 - Coronary artery disease and factor VII hyperactivity in elderly Japanese

AU - Kario, Kazuomi

AU - Matsuo, Takefumi

N1 - Funding Information: From the Department of Internal Medicine, Hyogo Prefectural Awaji Hospital and Awaji-Hokutan Public Clinic, Hyogo, Japan. This study was supported in part by a grant from the Foundation for the Development of the Community, Tochigi, Japan. Dr. Kario’s addressi s: 480-2, Ikuha, Hokutan-chyo, Tsuna-gun, Hyogo-ken, 656-16, Japan. Manuscript received September 9, 1991; revised manuscript received and accepted November 14, 1991 .

PY - 1992/3/15

Y1 - 1992/3/15

N2 - High levels of factor VII (FVII) coagulant activity (FVIIc) have been associated with an increased risk of coronary artery disease and cardiac death, and are thought to be of greater significance than cholesterol in the first 5 years after screening.1 These studies have mainly been performed in Western countries and the subjects were generally adults aged <65 years. Japan is one of the countries where the incidence of coronary artery disease is low,2 and we have recently reported on FVII hyperactivity in the elderly Japanese.3 This time, to study the relation between coronary artery disease and FVII in elderly Japanese persons, we performed electrocardiography and measured FVIIc and FVII antigen (FVIIag) levels as well as blood lipid fractions.

AB - High levels of factor VII (FVII) coagulant activity (FVIIc) have been associated with an increased risk of coronary artery disease and cardiac death, and are thought to be of greater significance than cholesterol in the first 5 years after screening.1 These studies have mainly been performed in Western countries and the subjects were generally adults aged <65 years. Japan is one of the countries where the incidence of coronary artery disease is low,2 and we have recently reported on FVII hyperactivity in the elderly Japanese.3 This time, to study the relation between coronary artery disease and FVII in elderly Japanese persons, we performed electrocardiography and measured FVIIc and FVII antigen (FVIIag) levels as well as blood lipid fractions.

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DO - 10.1016/0002-9149(92)90511-V

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SN - 0002-9149

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JO - American Journal of Cardiology

JF - American Journal of Cardiology

IS - 8

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Coronary artery disease and factor VII hyperactivity in elderly Japanese

Abstract

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