Coronary artery disease and exercise induced changes in the P wave in the EKG

Roberto F. Pereira, U. Tekin, V. Nair, A. P. Niarchos, E. Guzman, T. J. Sacchi, B. C. Vasavada

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: We analyzed the effects of exercise in the amplitude of the P wave in the lead V1 of the surface EKG. Our purpose was to investigate the correlation between the presence of coronary artery disease and exercise induced changes in the amplitude of the P wave in V1. Methods: P wave amplitude in lead V1 at rest and peak exercise was measured in the EKGs of 30 patients referred for exercise treadmill stress test who had positive results and underwent subsequent cardiac catheterization. The difference between p wave amplitude before and after exercise was calculated. The patients were divided in two groups according to the presence or absence of significant coronary artery disease, defined as presence of obstruction of at least 70% in one of the coronary arteries. The values obtained for each group were ranked in ascending order and mean ranks were computed. Statistical analysis was performed using the Mann-Whitney test. Results: See Table. Analysis of the mean and sum of ranks using Mann-Whitney test resulted in a U value of 43.500, which corresponds to a p value of .004 Conclusions: Patients with coronary artery disease show a significant difference in the exercise induced changes in the amplitude of the P wave in lead V1 when compared with patients without coronary artery disease. Clinical Implications: This finding may prove to be useful in the diagnosis of coronary artery disease. CAD number of pts MEAN RANK SUM OF RANKS YES 17 19.44 330.50 NO 13 10.35 134.50 TOTAL 30.

Original languageEnglish
Pages (from-to)317S
JournalChest
Volume114
Issue number4 SUPPL.
StatePublished - Oct 1998

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