TY - JOUR
T1 - Corneal hysteresis and beta-zone parapapillary atrophy
AU - Hayes, Daniel D.
AU - Teng, Christopher C.
AU - De Moraes, Carlos Gustavo
AU - Tello, Celso
AU - Liebmann, Jeffrey M.
AU - Ritch, Robert
N1 - Funding Information:
Publication of this article was supported by the Edward B. Goodnow Research Fund of The New York Glaucoma Research Institute, New York, New York. Celso Tello is a consultant for Diopsys Corporation and has received lecture fees from Alcon Laboratories and Allergan, Inc. Jeffrey M. Liebmann is a consultant for Alcon Laboratories, Allergan, Inc, Diopsys Corporation, Optovue, Inc, Quark Pharmaceuticals, Inc, and Topcon Medical Systems; and has received grant support from Carl Zeiss Meditec , Diopsys Corporation , Heidelberg Engineering , Optovue, Inc , and Topcon Medical Systems . Robert Ritch is a consultant for Aeon, Astron, and Isonic; has received lecture fees from Merck; and holds a patent interest with Ocular Instruments. Involved in design and conduct of the study (D.D.H., C.C.T., C.G.D., C.T., J.M.L., R.R.); collection, management, analysis, and interpretation of data (D.D.H., C.C.T., C.G.D.); and preparation, review, or approval of the manuscript (D.D.H., C.C.T., C.G.D., C.T., J.M.L., R.R.). The study was prospectively approved by the New York Eye and Ear Infirmary Institutional Review Board and followed the tenets of the Declaration of Helsinki.
PY - 2012/2
Y1 - 2012/2
N2 - Purpose: To evaluate the relationship between β-zone parapapillary atrophy (βPPA) and corneal hysteresis (CH) in patients with glaucoma. Design: Prospective, cross-sectional study. Methods: Glaucoma patients aged 18 to 90 years with disc photographs within 12 months of the study visit were consecutively enrolled. Exclusion criteria included ocular surgery other than clear corneal phacoemulsification, myopia >6 diopters, contact lens use, and corneal abnormality. CH was measured using the Ocular Response Analyzer (ORA). Disc photographs were evaluated in a masked fashion for βPPA. Results: We enrolled 99 patients (mean age 67.6 years; 45 men, 54 women). Univariate analysis showed no significant difference in CH between eyes with and without βPPA (8.72 ± 0.23 vs 8.15 ± 0.27 mm Hg, P =.11). There were no differences in corneal resistance factor (CRF) (P =.47), central corneal thickness (CCT) (P =.11), ORA wave score (P =.23), age (P =.23), sex (P =.40), IOP (P =.86), or visual field mean deviation (VFMD) (P =.45). Eyes with βPPA were more myopic (-1.49 ± 0.27 vs -0.22 ± 0.31 diopters, P =.003). Multivariate analysis showed no significant difference in CH between eyes with and without βPPA (P =.38). Eyes with asymmetric βPPA also showed no significant difference in CH (8.97 ± 0.22 vs 9.10 ± 0.22 mm Hg, P =.69). Conclusions: We found no significant differences in CH between eyes with and without βPPA or between fellow eyes with asymmetric βPPA.
AB - Purpose: To evaluate the relationship between β-zone parapapillary atrophy (βPPA) and corneal hysteresis (CH) in patients with glaucoma. Design: Prospective, cross-sectional study. Methods: Glaucoma patients aged 18 to 90 years with disc photographs within 12 months of the study visit were consecutively enrolled. Exclusion criteria included ocular surgery other than clear corneal phacoemulsification, myopia >6 diopters, contact lens use, and corneal abnormality. CH was measured using the Ocular Response Analyzer (ORA). Disc photographs were evaluated in a masked fashion for βPPA. Results: We enrolled 99 patients (mean age 67.6 years; 45 men, 54 women). Univariate analysis showed no significant difference in CH between eyes with and without βPPA (8.72 ± 0.23 vs 8.15 ± 0.27 mm Hg, P =.11). There were no differences in corneal resistance factor (CRF) (P =.47), central corneal thickness (CCT) (P =.11), ORA wave score (P =.23), age (P =.23), sex (P =.40), IOP (P =.86), or visual field mean deviation (VFMD) (P =.45). Eyes with βPPA were more myopic (-1.49 ± 0.27 vs -0.22 ± 0.31 diopters, P =.003). Multivariate analysis showed no significant difference in CH between eyes with and without βPPA (P =.38). Eyes with asymmetric βPPA also showed no significant difference in CH (8.97 ± 0.22 vs 9.10 ± 0.22 mm Hg, P =.69). Conclusions: We found no significant differences in CH between eyes with and without βPPA or between fellow eyes with asymmetric βPPA.
UR - https://www.scopus.com/pages/publications/84855998466
U2 - 10.1016/j.ajo.2011.06.025
DO - 10.1016/j.ajo.2011.06.025
M3 - Article
AN - SCOPUS:84855998466
SN - 0002-9394
VL - 153
SP - 358-362.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 2
ER -