Corneal anesthesia induced by soaps and surfactants, lack of correlation in rabbits and humans

Laurence S. Harris, Yaffa Kahanowicza, Mitsugu Shimmyo

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Five commonly marketed bath and facial soaps and four commercially available hair shampoos were studied for their anesthetic effect on human and rabbit corneas. These compounds all produced anesthesia comparable to that induced by tetracaine hydrochloride 0.5% but lasting several hours longer in rabbits. None o f the soaps or shampoos produced corneal anesthesia in humans. Studies of corneal anesthesia in rabbits may not be extrapolated to the human eye.

Original languageEnglish
Pages (from-to)320-325
Number of pages6
JournalOphthalmologica
Volume170
Issue number4
DOIs
StatePublished - 1975
Externally publishedYes

Fingerprint

Dive into the research topics of 'Corneal anesthesia induced by soaps and surfactants, lack of correlation in rabbits and humans'. Together they form a unique fingerprint.

Cite this