Cord blood stem cell therapy for acquired immune deficiency syndrome

Gabriel Gonzalez, Elizabeth J. Shpall, Joseph C. Gathe, Richard R. Behringer, Malgorzata Simm, Ghalib Alkhatib

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Cord blood stem cell transplantation is routinely used to treat hematopoietic diseases. Individuals who are homozygous for the Δ32 polymorphism of the CCR5 locus, encoding a co-receptor for HIV-1, are normal and are resistant to HIV infection. Here we suggest that public cord blood repositories are likely to contain CCR5 homozygous units that could be used as a therapy for HIV-infected individuals.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalStem Cells and Development
Volume18
Issue number1
DOIs
StatePublished - 1 Jan 2009
Externally publishedYes

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