Abstract
The mechanisms whereby the gut mucosa tolerates trillions of commensal bacteria without developing inflammation remain poorly understood. A recent Science article reveals that gut innate lymphoid cells constrain inflammatory T cell responses to commensal bacteria by adopting a strategy usually deployed by thymic epithelial cells to negatively select self-reactive T cells.
Original language | English |
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Pages (from-to) | 991-992 |
Number of pages | 2 |
Journal | Cell Research |
Volume | 25 |
Issue number | 9 |
DOIs | |
State | Published - 4 Sep 2015 |