Abstract
Cholesterol-3-(3)H,4-(14)C was injected intravenously in man and its transformation to cholestanol was studied. From the (3)H: (14)C ratios in cholestanol isolated from blood, evidence for the participation of a ketonic intermediate in the conversion was obtained. In a second subject given cholestanol-3-(3)H,4-(14)C the (3)H: (14)C ratios in blood sterols remained unchanged for as long as 1 wk after the injection, which showed that cholestanol did not lose tritium by interconversion with cholestanone.
Original language | English |
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Pages (from-to) | 16-23 |
Number of pages | 8 |
Journal | Journal of Lipid Research |
Volume | 8 |
Issue number | 1 |
State | Published - Jan 1967 |
Externally published | Yes |