Control of polycythaemia vera with photochemotherapy in a patient with cutaneous T‐cell lymphoma

Carolyn Cottrill; Alex Geller; Francis X. DiSpaltro; Bennett Weissglass; Albert S. Klainer; Emil Bisaccia

doi:10.1111/j.1365-2141.1994.tb03286.x

Control of polycythaemia vera with photochemotherapy in a patient with cutaneous T‐cell lymphoma

Carolyn Cottrill, Alex Geller, Francis X. DiSpaltro, Bennett Weissglass, Albert S. Klainer, Emil Bisaccia

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Abstract

We report the use of photochemotherapy in a patient with polycythaemia vera (PV) and cutaneous T‐cell lymphoma (CTCL). The patient was diagnosed with PV and required monthly phlebotomy. Subsequently he was diagnosed with CTCL and was started on photochemotherapy. A clinical improvement in both conditions, with haematocrit stabilizing at a level of 50%, eliminated the need for further phlebotomy. It is conceiveable that photochemotherapy induced the clinical and laboratory improvement in PV by targeting the aberrant clonal haemopoietic cell, similar to the mechanism thought to be operative in CTCL, a clonal helper T cell malignancy.

Original language	English
Pages (from-to)	225-226
Number of pages	2
Journal	British Journal of Haematology
Volume	86
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2141.1994.tb03286.x
State	Published - Jan 1994
Externally published	Yes

Keywords

cutaneous T‐cell lymphoma
photochemotherapy
polycythaemia vera

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10.1111/j.1365-2141.1994.tb03286.x

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title = "Control of polycythaemia vera with photochemotherapy in a patient with cutaneous T‐cell lymphoma",

abstract = "We report the use of photochemotherapy in a patient with polycythaemia vera (PV) and cutaneous T‐cell lymphoma (CTCL). The patient was diagnosed with PV and required monthly phlebotomy. Subsequently he was diagnosed with CTCL and was started on photochemotherapy. A clinical improvement in both conditions, with haematocrit stabilizing at a level of 50%, eliminated the need for further phlebotomy. It is conceiveable that photochemotherapy induced the clinical and laboratory improvement in PV by targeting the aberrant clonal haemopoietic cell, similar to the mechanism thought to be operative in CTCL, a clonal helper T cell malignancy.",

keywords = "cutaneous T‐cell lymphoma, photochemotherapy, polycythaemia vera",

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AU - DiSpaltro, Francis X.

AU - Weissglass, Bennett

AU - Klainer, Albert S.

AU - Bisaccia, Emil

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N2 - We report the use of photochemotherapy in a patient with polycythaemia vera (PV) and cutaneous T‐cell lymphoma (CTCL). The patient was diagnosed with PV and required monthly phlebotomy. Subsequently he was diagnosed with CTCL and was started on photochemotherapy. A clinical improvement in both conditions, with haematocrit stabilizing at a level of 50%, eliminated the need for further phlebotomy. It is conceiveable that photochemotherapy induced the clinical and laboratory improvement in PV by targeting the aberrant clonal haemopoietic cell, similar to the mechanism thought to be operative in CTCL, a clonal helper T cell malignancy.

AB - We report the use of photochemotherapy in a patient with polycythaemia vera (PV) and cutaneous T‐cell lymphoma (CTCL). The patient was diagnosed with PV and required monthly phlebotomy. Subsequently he was diagnosed with CTCL and was started on photochemotherapy. A clinical improvement in both conditions, with haematocrit stabilizing at a level of 50%, eliminated the need for further phlebotomy. It is conceiveable that photochemotherapy induced the clinical and laboratory improvement in PV by targeting the aberrant clonal haemopoietic cell, similar to the mechanism thought to be operative in CTCL, a clonal helper T cell malignancy.

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Control of polycythaemia vera with photochemotherapy in a patient with cutaneous T‐cell lymphoma

Abstract

Keywords

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