Control of polycythaemia vera with photochemotherapy in a patient with cutaneous T‐cell lymphoma

Carolyn Cottrill, Alex Geller, Francis X. DiSpaltro, Bennett Weissglass, Albert S. Klainer, Emil Bisaccia

Research output: Contribution to journalArticlepeer-review

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Abstract

We report the use of photochemotherapy in a patient with polycythaemia vera (PV) and cutaneous T‐cell lymphoma (CTCL). The patient was diagnosed with PV and required monthly phlebotomy. Subsequently he was diagnosed with CTCL and was started on photochemotherapy. A clinical improvement in both conditions, with haematocrit stabilizing at a level of 50%, eliminated the need for further phlebotomy. It is conceiveable that photochemotherapy induced the clinical and laboratory improvement in PV by targeting the aberrant clonal haemopoietic cell, similar to the mechanism thought to be operative in CTCL, a clonal helper T cell malignancy.

Original languageEnglish
Pages (from-to)225-226
Number of pages2
JournalBritish Journal of Haematology
Volume86
Issue number1
DOIs
StatePublished - Jan 1994
Externally publishedYes

Keywords

  • cutaneous T‐cell lymphoma
  • photochemotherapy
  • polycythaemia vera

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