Contrast-Induced Acute Kidney Injury—Definitions, Epidemiology, and Implications

Lorenzo Azzalini, Sanjog Kalra

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Contrast-induced acute kidney injury (CI-AKI) is the acute onset of renal injury following exposure to iodinated contrast media. Several definitions have been used, which complicates the estimation of the epidemiological relevance of this condition and comparisons in outcome research. The incidence of CI-AKI increases as a function of patient and procedure complexity in coronary, endovascular, and structural interventions. CI-AKI is associated with a high burden of short- and long-term adverse events, and leads to increased healthcare costs. This review will provide an overview of the definitions, epidemiology, and implications of CI-AKI in patients undergoing coronary, endovascular, and structural catheter-based procedures.

Original languageEnglish
Pages (from-to)299-309
Number of pages11
JournalInterventional Cardiology Clinics
Issue number3
StatePublished - Jul 2020


  • Contrast media
  • Contrast-induced acute kidney injury
  • Contrast-induced nephropathy
  • Epidemiology


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