Contemporary management of localized penile cancer

David Shapiro, Daniel Shasha, Mohiba Tareen, Basir Tareen

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

This article reviews the etiology, clinical presentation and diagnosis of localized penile cancer. We summarize the current literature concerning recent trends and advances in the treatment of localized penile cancer (<T2, node negative [N0]) through the use of a systematic review and meta-analysis. We discuss a generalized overview of the current treatment options. A total of 54 review articles, retrospective studies and case reports on conservative penile treatments were reviewed and screened for data on the efficacy of numerous therapies in carcinoma in situ, T1N0 and T2N0 patients. These data were analyzed, tabulated and discussed. Even though recurrence rates are higher in patients receiving penile-sparing options (compared with patients receiving radical penectomy), the locally recurrent cancers are highly treatable and these patients experience a higher quality of life.

Original languageEnglish
Pages (from-to)29-36
Number of pages8
JournalExpert Review of Anticancer Therapy
Volume11
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

Keywords

  • partial penectomy
  • penile CIS
  • penile cancer
  • penile-sparing surgery

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