Consequences of chronic hepatitis C: A review article for the hematologist

Louis M. Aledort

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

The hepatitis C virus (HCV) has been cloned, and assays capable of detecting antibody to HCV recombinant proteins (anti‐HCV) have been developed. Concurrent with the cloning and development of the anti‐HCV screening tests, trials with interferon alfa‐2b have documented biochemical and histologic improvement in the indices of hepatitis C and non‐A, non‐B (NANB) in patients who were chronically infected. Subsequently, the anti‐HCV assays and interferon alfa‐2b have become clinically available. These new detection and treatment modalities can now be used in the management of hemophilics and other chronically transfused patients who bear great risk for blood‐borne infections and manifest signs of chronic hepatitis. © 1993 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)29-37
Number of pages9
JournalAmerican Journal of Hematology
Volume44
Issue number1
DOIs
StatePublished - Sep 1993

Keywords

  • HCV
  • hemophilia
  • hepatitis
  • hepatitis C
  • hepatitis C virus

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