Consensus workshop on the toxic effects of long-term PUVA therapy

Warwick L. Morison, Richard D. Baughman, Robert M. Day, P. Donald Forbes, Herbert Hoenigsmann, Gerald G. Krueger, Mark Lebwohl, Robert Lew, Luigi Naldi, John A. Parrish, Michael Piepkom, Robert S. Stern, Gerald D. Weinstein, S. Elizabeth Whitmore

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120 Scopus citations


The possibility that there is an increased risk of melanoma in patients with psoriasis treated with psoralen-UV-A (PUVA) therapy has raised concern on the part of physicians and patients about the long-term safety of this treatment. In response to this concern, the National Psoriasis Foundation sponsored a workshop at which invited participants with expertise in PUVA therapy, psoriasis treatment, melanoma and nonmelanoma skin cancer, and epidemiological and clinical trials were asked to develop a consensus on the following 3 issues: the risk of long-term adverse effects of PUVA therapy with emphasis on nonmelanoma and melanoma skin cancer; the guidelines for physicians and patients for selection and use of PUVA therapy with consideration of the risk-benefit ratio of this treatment compared with the risk-benefit ratios of alternative treatments; and the directions for further evaluation of the long-term effects of PUVA therapy.

Original languageEnglish
Pages (from-to)595-598
Number of pages4
JournalArchives of Dermatology
Issue number5
StatePublished - 1998


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