Conducting metagenomic studies in microbiology and clinical research

Tiphaine C. Martin, Alessia Visconti, Tim D. Spector, Mario Falchi

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations

Abstract

Owing to the increased cost-effectiveness of high-throughput technologies, the number of studies focusing on the human microbiome and its connections to human health and disease has recently surged. However, best practices in microbiology and clinical research have yet to be clearly established. Here, we present an overview of the challenges and opportunities involved in conducting a metagenomic study, with a particular focus on data processing and analytical methods.

Original languageEnglish
Pages (from-to)8629-8646
Number of pages18
JournalApplied Microbiology and Biotechnology
Volume102
Issue number20
DOIs
StatePublished - 1 Oct 2018

Keywords

  • Human microbiome
  • Metagenomics
  • Microbiology and clinical research
  • Next generation sequencing

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