@article{2406306b16e447e79162b1563c12804c,
title = "Conducting an Oral Food Challenge to Peanut in an Infant",
abstract = "Results from the Learning Early About Peanut trial and its follow-up study suggest that early peanut introduction in the diets of high-risk infants may prevent the development of peanut allergy. Allergy organizations around the world released a unified statement, the Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High Risk Infants, in response to results from the Learning Early About Peanut trial, which recommends early introduction of peanut into the diet of those children at greatest risk of development of peanut allergy. As a result, it is expected that practicing allergists will experience an increased demand to perform an oral food challenge (OFC) in infants. Allergists often perform OFCs; however, conducting an OFC in an infant creates unique circumstances that have not been considered in previously published OFC guideline documents. The purpose of this workgroup report is to provide guidance to practitioners regarding the proper approach for conducting a peanut challenge in an infant.",
keywords = "Early introduction, Food allergy, Infant, LEAP, Oral food challenge, Peanut allergy",
author = "Bird, {J. Andrew} and Marion Groetch and Allen, {Katrina J.} and Bock, {S. Allan} and Stephanie Leonard and Nowak-Wegrzyn, {Anna H.} and Scott Sicherer and April Clark and Fleischer, {David M.} and Carina Venter and Brian Vickery and Young, {Michael C.}",
note = "Funding Information: Conflicts of interest: J. A. Bird is a board member for Food Allergy Research and Education (FARE); has consultancy arrangements with Aimmune Therapeutics and Wedbush Consulting; has received one or more grants from or has one or more grants pending with Aimmune Therapeutics, DBV Technologies, the Foundation of the American College of Allergy, Asthma and Immunology, and Nestle Health Sciences; has received one or more payments for lecturing from or is on the speakers{\textquoteright} bureau for Nutricia North America and DBV Technologies; and has received one or more payments for manuscript preparation from the Eastern Allergy Conference. M. Groetch has received one or more payments for lecturing from or is on the speakers{\textquoteright} bureau for Nutricia North America and has received royalties from UpToDate. K. J. Allen has received one or more consulting fees or honoraria from Nestle, ThermoFisher, Aspencare, and Nutricia. S. A. Bock is employed by Boulder Valley Asthma and Allergy Clinic and has received royalties from UpToDate. S. Leonard is a Board member for and has received one or more payments for travel/accommodations/meeting expenses from FARE, has received one or more grants from or has one or more grants pending with Rady Children's Hospital, has received one or more payments for lecturing from or is on the speakers' bureau for the Allergy & Asthma Medical Group, and was site investigator for sponsored trials for Aimmune and DBV Technologies. A. H. Nowak-Wegrzyn is Chair of the Medical Advisory Board for International FPIES Association and member of the data monitoring committee for Merck; is employed by Icahn School of Medicine; has received one or more grants from or has one or more grants pending with Immune Tolerance Network, FARE, DBV Technologies, Nestle, and Nutricia; has received one or more payments for lecturing from or is on the speakers' bureau for ThermoFisher and Nestle; has received royalties from UpToDate; and has received one or more payments for the development of educational presentations for Annenberg. S. Sicherer has received royalties from UpToDate and is the Associate Editor of The Journal of Allergy and Clinical Immunology: In Practice. D. M. Fleischer has received travel support from the National Institute of Allergy and Infectious Diseases; is on the National Peanut Board, Food Allergy & Anaphylaxis Connection Team Medical Advisory Board, and FARE Medical Advisory Board; has received consultancy fees from LabCorp, INSYS Therapeutics Inc, and Adamis Pharmaceuticals Corporation; is employed by University Physicians Inc; has received research support from Monsanto Company, Nestle Nutrition Institute, and DBV Technologies; has received lecture fees from Nestle Nutrition Institute, Canadian Society of Allergy and Clinical Immunology, and American College of Allergy, Asthma, and Immunology; has received payment for manuscript preparation from Nestle Nutrition Institute; and receives royalties from UpToDate. C. Venter has received consultancy fees from Mead Johnson; has received research support from the National Institutes of Health; and has received lecture fees from Danone. B. Vickery is employed by and owns stock/stock options in Aimmune. The rest of the authors declare that they have no relevant conflicts of interest. Publisher Copyright: {\textcopyright} 2016 American Academy of Allergy, Asthma & Immunology",
year = "2017",
month = apr,
day = "1",
doi = "10.1016/j.jaip.2016.07.019",
language = "English",
volume = "5",
pages = "301--311.e1",
journal = "Journal of Allergy and Clinical Immunology: In Practice",
issn = "2213-2198",
publisher = "Elsevier",
number = "2",
}