Conducting an Oral Food Challenge to Peanut in an Infant

J. Andrew Bird, Marion Groetch, Katrina J. Allen, S. Allan Bock, Stephanie Leonard, Anna H. Nowak-Wegrzyn, Scott Sicherer, April Clark, David M. Fleischer, Carina Venter, Brian Vickery, Michael C. Young

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Results from the Learning Early About Peanut trial and its follow-up study suggest that early peanut introduction in the diets of high-risk infants may prevent the development of peanut allergy. Allergy organizations around the world released a unified statement, the Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High Risk Infants, in response to results from the Learning Early About Peanut trial, which recommends early introduction of peanut into the diet of those children at greatest risk of development of peanut allergy. As a result, it is expected that practicing allergists will experience an increased demand to perform an oral food challenge (OFC) in infants. Allergists often perform OFCs; however, conducting an OFC in an infant creates unique circumstances that have not been considered in previously published OFC guideline documents. The purpose of this workgroup report is to provide guidance to practitioners regarding the proper approach for conducting a peanut challenge in an infant.

Original languageEnglish
Pages (from-to)301-311.e1
JournalJournal of Allergy and Clinical Immunology: In Practice
Issue number2
StatePublished - 1 Apr 2017


  • Early introduction
  • Food allergy
  • Infant
  • LEAP
  • Oral food challenge
  • Peanut allergy


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