Concentration of clindamycin in human bone

P. Nicholas; B. R. Meyers; R. N. Levy; S. Z. Hirschman

doi:10.1128/AAC.8.2.220

Concentration of clindamycin in human bone

P. Nicholas
, B. R. Meyers
, R. N. Levy
, S. Z. Hirschman

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 ± 3.37 μg/ml in serum and 2.63 ± 1.76 μg/g in bone; mean ratio of bone serum concentration was 0.40 ± 0.30.

Original language	English
Pages (from-to)	220-221
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	8
Issue number	2
DOIs	https://doi.org/10.1128/AAC.8.2.220
State	Published - 1975
Externally published	Yes

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@article{38e68250a90b4ac38361f5d396f13b6c,

title = "Concentration of clindamycin in human bone",

abstract = "Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 ± 3.37 μg/ml in serum and 2.63 ± 1.76 μg/g in bone; mean ratio of bone serum concentration was 0.40 ± 0.30.",

author = "P. Nicholas and Meyers, \{B. R.\} and Levy, \{R. N.\} and Hirschman, \{S. Z.\}",

year = "1975",

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language = "English",

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T1 - Concentration of clindamycin in human bone

AU - Nicholas, P.

AU - Meyers, B. R.

AU - Levy, R. N.

AU - Hirschman, S. Z.

PY - 1975

Y1 - 1975

N2 - Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 ± 3.37 μg/ml in serum and 2.63 ± 1.76 μg/g in bone; mean ratio of bone serum concentration was 0.40 ± 0.30.

AB - Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 ± 3.37 μg/ml in serum and 2.63 ± 1.76 μg/g in bone; mean ratio of bone serum concentration was 0.40 ± 0.30.

UR - https://www.scopus.com/pages/publications/0016731884

U2 - 10.1128/AAC.8.2.220

DO - 10.1128/AAC.8.2.220

M3 - Article

C2 - 1180546

AN - SCOPUS:0016731884

SN - 0066-4804

VL - 8

SP - 220

EP - 221

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 2

ER -

Concentration of clindamycin in human bone

Abstract

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