Concentration of clindamycin in human bone

P. Nicholas, B. R. Meyers, R. N. Levy, S. Z. Hirschman

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 ± 3.37 μg/ml in serum and 2.63 ± 1.76 μg/g in bone; mean ratio of bone serum concentration was 0.40 ± 0.30.

Original languageEnglish
Pages (from-to)220-221
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Issue number2
StatePublished - 1975
Externally publishedYes


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