TY - JOUR
T1 - Con
T2 - Alcohol Abstinence does not Impact Post-Transplant Outcomes in ALD and AAH
AU - Stoffel, Elina
AU - Im, Gene Y.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.
PY - 2025/12
Y1 - 2025/12
N2 - Purpose of Review: In this debate, we will argue that abstinence remains a relevant, evidence-based, and ethically necessary goal after LT for ALD not only because of its effect on graft and patient survival, but because of its broader impact on risk stratification, healthcare equity, and long-term quality of life. Recent Findings: Abstinence is a critical goal after LT for ALD and AH because: 1) alcohol relapse after LT for ALD is the strongest predictor of graft failure and mortality, 2) alcohol relapse after LT for ALD worsens health risks beyond the liver, 3) abstinence upholds ethical principles and public trust. Summary: In this debate, we have argued that abstinence remains a relevant, evidence-based, and ethically necessary goal after LT for ALD that is a key driver of positive post-LT outcomes.
AB - Purpose of Review: In this debate, we will argue that abstinence remains a relevant, evidence-based, and ethically necessary goal after LT for ALD not only because of its effect on graft and patient survival, but because of its broader impact on risk stratification, healthcare equity, and long-term quality of life. Recent Findings: Abstinence is a critical goal after LT for ALD and AH because: 1) alcohol relapse after LT for ALD is the strongest predictor of graft failure and mortality, 2) alcohol relapse after LT for ALD worsens health risks beyond the liver, 3) abstinence upholds ethical principles and public trust. Summary: In this debate, we have argued that abstinence remains a relevant, evidence-based, and ethically necessary goal after LT for ALD that is a key driver of positive post-LT outcomes.
KW - Abstinence
KW - Alcohol-associated cirrhosis
KW - Cancer
KW - Liver transplantation
KW - Relapse
KW - Survival
UR - https://www.scopus.com/pages/publications/105022725528
U2 - 10.1007/s11901-025-00716-4
DO - 10.1007/s11901-025-00716-4
M3 - Review article
AN - SCOPUS:105022725528
SN - 1540-3416
VL - 24
JO - Current Hepatology Reports
JF - Current Hepatology Reports
IS - 1
M1 - 40
ER -