Abstract
A morphometric study of 11 pleural malignant mesotheliomas and 11 pleural reactive mesothelial proliferations is reported. Pleural biopsy specimens of these lesions were studied with a new system of video-based computerized interactive morphometry that allows the comparison of real-time images of nuclear profiles with computer-generated graphic standards for the purpose of estimating their diameters. Malignant mesotheliomas had nuclear profile diameters (NPDs) ranging from 4 to 14 μm and a mean NPD of 9.6 ± 0.5 μm. Reactive mesothelial proliferations had NPDs ranging from 4 to 12 μm, but exhibited a significantly smaller mean NPD of 6.4 ± 0.2 μm. The potential technical advantages of computerized interactive morphometry over other morphometric methods are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 1102-1105 |
| Number of pages | 4 |
| Journal | Archives of Pathology and Laboratory Medicine |
| Volume | 109 |
| Issue number | 12 |
| State | Published - 1985 |
| Externally published | Yes |