TY - JOUR
T1 - Complications of continuous-flow mechanical circulatory support devices
AU - Patel, Harsh
AU - Madanieh, Raef
AU - Kosmas, Constantine E.
AU - Vatti, Satya K.
AU - Vittorio, Timothy J.
N1 - Publisher Copyright:
© the authors, publisher and licensee Libertas Academica Limited.
PY - 2014/12/6
Y1 - 2014/12/6
N2 - Left ventricular assist devices (LVADs), more importantly the continuous-flow subclass, have revolutionized the medical field by improving New York Heart Association (NYHA) functional class status, quality of life, and survival rates in patients with advanced systolic heart failure. From the first pulsatile device to modern day continuous-flow devices, LVADs have continued to improve, but they are still associated with several complications. These complications include infection, bleeding, thrombosis, hemolysis, aortic valvular dysfunction, right heart failure, and ventricular arrhythmias. In this article, we aim to review these complications to understand the most appropriate approach for their prevention and to discuss the available therapeutic modalities.
AB - Left ventricular assist devices (LVADs), more importantly the continuous-flow subclass, have revolutionized the medical field by improving New York Heart Association (NYHA) functional class status, quality of life, and survival rates in patients with advanced systolic heart failure. From the first pulsatile device to modern day continuous-flow devices, LVADs have continued to improve, but they are still associated with several complications. These complications include infection, bleeding, thrombosis, hemolysis, aortic valvular dysfunction, right heart failure, and ventricular arrhythmias. In this article, we aim to review these complications to understand the most appropriate approach for their prevention and to discuss the available therapeutic modalities.
KW - Aortic insufficiency
KW - Bleeding
KW - Continuous-flow
KW - Infection
KW - Left ventricular assist device
KW - Pulsatile-flow
KW - Right ventricular failure
KW - Thrombosis
KW - Ventricular arrhythmias
UR - https://www.scopus.com/pages/publications/84930508331
U2 - 10.4137/CMC.S19708
DO - 10.4137/CMC.S19708
M3 - Article
AN - SCOPUS:84930508331
SN - 1179-5468
VL - 9
SP - 15
EP - 21
JO - Clinical Medicine Insights: Cardiology
JF - Clinical Medicine Insights: Cardiology
ER -