TY - JOUR
T1 - Complexities of diagnosis and treatment of allergic respiratory disease in the elderly
AU - Busse, Paula J.
AU - Kilaru, Kiran
N1 - Funding Information:
Paula J. Busse was supported by a K08 NIH grant. No other sources of funding were used to assist in the preparation of this review. The authors have no conflicts of interest that are directly relevant to the content of this review.
PY - 2009
Y1 - 2009
N2 - Atopic diseases such as rhinitis and asthma are relatively common in children and young adults. However, many patients aged >65 years are also affected by these disorders. Indeed, the literature suggests that between 3-12% and 4-13% of individuals in this age range have allergic rhinitis and asthma, respectively. However, these numbers are most likely underestimates because atopic diseases are frequently not considered in older patients. The diagnosis of both allergic rhinitis and asthma in older patients is more difficult than in younger patients because of a wide differential diagnosis of other diseases that can produce similar symptoms and must be excluded. Furthermore, treatment of these disorders is complicated by the potential for drug interactions, concern about the adverse effects of medications, in particular corticosteroids, and the lack of drug trials specifically targeting treatment of older patients with allergic rhinitis and asthma.
AB - Atopic diseases such as rhinitis and asthma are relatively common in children and young adults. However, many patients aged >65 years are also affected by these disorders. Indeed, the literature suggests that between 3-12% and 4-13% of individuals in this age range have allergic rhinitis and asthma, respectively. However, these numbers are most likely underestimates because atopic diseases are frequently not considered in older patients. The diagnosis of both allergic rhinitis and asthma in older patients is more difficult than in younger patients because of a wide differential diagnosis of other diseases that can produce similar symptoms and must be excluded. Furthermore, treatment of these disorders is complicated by the potential for drug interactions, concern about the adverse effects of medications, in particular corticosteroids, and the lack of drug trials specifically targeting treatment of older patients with allergic rhinitis and asthma.
KW - Allergic rhinitis, general
KW - Antihistamines, therapeutic use
KW - Asthma, general
KW - Beta 2 adrenergic receptor agonists, therapeutic use
KW - Corticosteroids, therapeutic use
KW - Decongestants, therapeutic use
KW - Elderly
KW - Leukotriene modulators, therapeutic use
UR - http://www.scopus.com/inward/record.url?scp=58149114639&partnerID=8YFLogxK
U2 - 10.2165/0002512-200926010-00001
DO - 10.2165/0002512-200926010-00001
M3 - Review article
C2 - 19102511
AN - SCOPUS:58149114639
SN - 1170-229X
VL - 26
SP - 1
EP - 22
JO - Drugs and Aging
JF - Drugs and Aging
IS - 1
ER -