Complex regional pain syndrome: a narrative review for the practising clinician

H. Shim, J. Rose, S. Halle, P. Shekane

Research output: Contribution to journalReview articlepeer-review

100 Scopus citations


Complex regional pain syndrome (CRPS) is a life-altering condition that usually affects the extremities after a trauma or nerve injury. The physiologic changes that occur as a result of the inciting injury are complex, as the name of the syndrome implies. The pain and disability associated with CRPS often lead to psychological co-morbidities that create a vicious cycle of pain, isolation, and depression. We review recent developments in the understanding of CRPS and advancements in management of this syndrome. Further research in targeting specific mechanisms involved in the pathophysiology of CRPS should lead to prevention of this condition.

Original languageEnglish
Pages (from-to)e424-e433
JournalBritish Journal of Anaesthesia
Issue number2
StatePublished - Aug 2019


  • CRPS
  • causalgia
  • chronic pain
  • reflex sympathetic dystrophy


Dive into the research topics of 'Complex regional pain syndrome: a narrative review for the practising clinician'. Together they form a unique fingerprint.

Cite this