Complement-fixing antigen of human sarcomas

Jitender Sethi; Yashar Hirshaut

doi:10.1093/jnci/57.3.489

Complement-fixing antigen of human sarcomas

Jitender Sethi
, Yashar Hirshaut

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Further investigation of the humoral immune responses of patients with sarcoma to their tumors revealed a sarcoma-associated antigen that was readily detected by complement fixation. Circulating levels of antibody to this antigen, tentatively labeled S₃, rose markedly after surgical removal ofthe tumor. Antibody to S₃, as to S₁ and S₂, was highly prevalent in patients with various malignant tumors other than sarcoma.

Original language	English
Pages (from-to)	489-493
Number of pages	5
Journal	Journal of the National Cancer Institute
Volume	57
Issue number	3
DOIs	https://doi.org/10.1093/jnci/57.3.489
State	Published - Sep 1976
Externally published	Yes

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title = "Complement-fixing antigen of human sarcomas",

abstract = "Further investigation of the humoral immune responses of patients with sarcoma to their tumors revealed a sarcoma-associated antigen that was readily detected by complement fixation. Circulating levels of antibody to this antigen, tentatively labeled S3, rose markedly after surgical removal ofthe tumor. Antibody to S3, as to S1 and S2, was highly prevalent in patients with various malignant tumors other than sarcoma.",

author = "Jitender Sethi and Yashar Hirshaut",

note = "Funding Information: 2 Supported in part by Public Health Service contract NOI CB53942 fro£? the Division of Cancer Biology and· Diagnosis, National Cancer Institute.",

year = "1976",

month = sep,

doi = "10.1093/jnci/57.3.489",

language = "English",

volume = "57",

pages = "489--493",

journal = "Journal of the National Cancer Institute",

issn = "0027-8874",

publisher = "Oxford University Press",

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T1 - Complement-fixing antigen of human sarcomas

AU - Sethi, Jitender

AU - Hirshaut, Yashar

N1 - Funding Information: 2 Supported in part by Public Health Service contract NOI CB53942 fro£? the Division of Cancer Biology and· Diagnosis, National Cancer Institute.

PY - 1976/9

Y1 - 1976/9

N2 - Further investigation of the humoral immune responses of patients with sarcoma to their tumors revealed a sarcoma-associated antigen that was readily detected by complement fixation. Circulating levels of antibody to this antigen, tentatively labeled S3, rose markedly after surgical removal ofthe tumor. Antibody to S3, as to S1 and S2, was highly prevalent in patients with various malignant tumors other than sarcoma.

AB - Further investigation of the humoral immune responses of patients with sarcoma to their tumors revealed a sarcoma-associated antigen that was readily detected by complement fixation. Circulating levels of antibody to this antigen, tentatively labeled S3, rose markedly after surgical removal ofthe tumor. Antibody to S3, as to S1 and S2, was highly prevalent in patients with various malignant tumors other than sarcoma.

UR - https://www.scopus.com/pages/publications/0017141768

U2 - 10.1093/jnci/57.3.489

DO - 10.1093/jnci/57.3.489

M3 - Article

C2 - 978761

AN - SCOPUS:0017141768

SN - 0027-8874

VL - 57

SP - 489

EP - 493

JO - Journal of the National Cancer Institute

JF - Journal of the National Cancer Institute

IS - 3

ER -

Complement-fixing antigen of human sarcomas

Abstract

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