Comparison of X-ray films and low-dose computed tomographic scans: Demonstration of asbestos-related changes in 2760 nuclear weapons workers screened for lung cancer

Albert Miller, Shannon A. Widman, Jeffrey A. Miller, Amy Manowitz, Steven B. Markowitz

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Objective: Increased availability and technical improvements of computed tomographic (CT) scanning encourages its use for detecting asbestos-related disease. We compared low-dose scans and x-ray films in 2760 workers potentially exposed to asbestos, to assess their ability to detect interstitial lung disease (ILD) and pleural thickening (PT). Methods: A total of 2760 nuclear workers received radiography and CT scanning (2006 to 2009). X-ray films were read by a B reader for ILD and PT and CT scans by a thoracic radiologist, using a protocol for nodules, ILD, and PT. Results: Of the 2760 workers, 271 showed circumscribed PT on CT scans, and 73 on x-ray films, 54 (74%) of which were confirmed on CT scans; 76 showed ILD on CT scans, and 15 on x-ray film, 10 (67%) of which were confirmed on CT scans. Conclusions: Radiographic readings of PT and ILD were generally confirmed on CT scans. Computed tomographic scans detected three to five times more cases; the majority were minor.

Original languageEnglish
Pages (from-to)741-745
Number of pages5
JournalJournal of Occupational and Environmental Medicine
Volume55
Issue number7
DOIs
StatePublished - Jul 2013
Externally publishedYes

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