TY - JOUR
T1 - Comparison of stereo disc photographs and alternation flicker using a novel matching technology for detecting glaucoma progression
AU - Radcliffe, Nathan M.
AU - Sehi, Mitra
AU - Wallace, Ira B.
AU - Greenfield, David S.
AU - Krupin, Theodore
AU - Ritch, Robert
PY - 2010/11
Y1 - 2010/11
N2 - ■ BACKGROUND AND OBJECTIVE: To compare agreement of automated alternation flicker and serial stereophotograph inspection for detection of progressive glaucoma. ■ PATIENTS AND METHODS: Serial photographs of patients with glaucoma with at least 36 months of follow-up and perimetry every 4 months were assessed by four graders using predefined criteria with both flicker and stereophotography. The main outcome measure was progressive neuroretinal rim deterioration as identified by each technique. ■ RESULTS: Forty eyes (20 patients) were included and 12 eyes progressed with perimetry. Using stereophotography, the overall agreement (kappa ± standard error) was 0.19 ± 0.06 for rim change, 0.78 ± 0.06 for disc hemorrhage, and -0.04 ± 0.06 for vessel movement. Using flicker, the overall agreement was similar for rim change (0.28 ± 0.06; P = .29), worse for disc hemorrhage (0.43 ± 0.06; P < .001), and better for vessel movement (0.22 ± 0.06; P = .002). The agreement between perimetric and disc progression was similar using stereophotography (0.10 ± 0.05) and flicker (0.19 ± 0.05; P = .20). ■ CONCLUSION: Agreement between flicker and stereophotography was similar.
AB - ■ BACKGROUND AND OBJECTIVE: To compare agreement of automated alternation flicker and serial stereophotograph inspection for detection of progressive glaucoma. ■ PATIENTS AND METHODS: Serial photographs of patients with glaucoma with at least 36 months of follow-up and perimetry every 4 months were assessed by four graders using predefined criteria with both flicker and stereophotography. The main outcome measure was progressive neuroretinal rim deterioration as identified by each technique. ■ RESULTS: Forty eyes (20 patients) were included and 12 eyes progressed with perimetry. Using stereophotography, the overall agreement (kappa ± standard error) was 0.19 ± 0.06 for rim change, 0.78 ± 0.06 for disc hemorrhage, and -0.04 ± 0.06 for vessel movement. Using flicker, the overall agreement was similar for rim change (0.28 ± 0.06; P = .29), worse for disc hemorrhage (0.43 ± 0.06; P < .001), and better for vessel movement (0.22 ± 0.06; P = .002). The agreement between perimetric and disc progression was similar using stereophotography (0.10 ± 0.05) and flicker (0.19 ± 0.05; P = .20). ■ CONCLUSION: Agreement between flicker and stereophotography was similar.
UR - http://www.scopus.com/inward/record.url?scp=79953233451&partnerID=8YFLogxK
U2 - 10.3928/15428877-20100830-02
DO - 10.3928/15428877-20100830-02
M3 - Article
C2 - 20839669
AN - SCOPUS:79953233451
SN - 1542-8877
VL - 41
SP - 629
EP - 634
JO - Ophthalmic Surgery Lasers and Imaging
JF - Ophthalmic Surgery Lasers and Imaging
IS - 6
ER -