Comparison of real-time PCR assays for monitoring serum hepatitis B virus DNA levels during antiviral therapy

Chee Kin Hui; Scott Bowden; Hai Ying Zhang; Anita Wong; Sharon Lewin; Frank Rousseau; Herve Mommeja-Marin; Nikki P. Lee; John M. Luk; Stephen Locarnini; Nancy Leung; Nikolai V. Naoumov; George K.K. Lau

doi:10.1128/JCM.02544-05

Comparison of real-time PCR assays for monitoring serum hepatitis B virus DNA levels during antiviral therapy

Chee Kin Hui, Scott Bowden, Hai Ying Zhang, Anita Wong, Sharon Lewin, Frank Rousseau, Herve Mommeja-Marin, Nikki P. Lee, John M. Luk, Stephen Locarnini, Nancy Leung, Nikolai V. Naoumov, George K.K. Lau

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The performance characteristics of the RealART and Molecular Beacons assays were compared with those of the Digene Hybrid Capture II assay (ultrasensitive). The results of the RealART and Digene Hybrid assays were related (r = 0.94; P < 0.001) and diverged by 2 orders of magnitude. The RealART assay can be used to effectively monitor serum hepatitis B virus DNA levels.

Original language	English
Pages (from-to)	2983-2987
Number of pages	5
Journal	Journal of Clinical Microbiology
Volume	44
Issue number	8
DOIs	https://doi.org/10.1128/JCM.02544-05
State	Published - Aug 2006
Externally published	Yes

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Hui, C. K., Bowden, S., Zhang, H. Y., Wong, A., Lewin, S., Rousseau, F., Mommeja-Marin, H., Lee, N. P., Luk, J. M., Locarnini, S., Leung, N., Naoumov, N. V., & Lau, G. K. K. (2006). Comparison of real-time PCR assays for monitoring serum hepatitis B virus DNA levels during antiviral therapy. Journal of Clinical Microbiology, 44(8), 2983-2987. https://doi.org/10.1128/JCM.02544-05

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author = "Hui, {Chee Kin} and Scott Bowden and Zhang, {Hai Ying} and Anita Wong and Sharon Lewin and Frank Rousseau and Herve Mommeja-Marin and Lee, {Nikki P.} and Luk, {John M.} and Stephen Locarnini and Nancy Leung and Naoumov, {Nikolai V.} and Lau, {George K.K.}",

year = "2006",

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doi = "10.1128/JCM.02544-05",

language = "English",

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AU - Hui, Chee Kin

AU - Bowden, Scott

AU - Zhang, Hai Ying

AU - Wong, Anita

AU - Lewin, Sharon

AU - Rousseau, Frank

AU - Mommeja-Marin, Herve

AU - Lee, Nikki P.

AU - Luk, John M.

AU - Locarnini, Stephen

AU - Leung, Nancy

AU - Naoumov, Nikolai V.

AU - Lau, George K.K.

PY - 2006/8

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AB - The performance characteristics of the RealART and Molecular Beacons assays were compared with those of the Digene Hybrid Capture II assay (ultrasensitive). The results of the RealART and Digene Hybrid assays were related (r = 0.94; P < 0.001) and diverged by 2 orders of magnitude. The RealART assay can be used to effectively monitor serum hepatitis B virus DNA levels.

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Comparison of real-time PCR assays for monitoring serum hepatitis B virus DNA levels during antiviral therapy

Abstract

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