Comparison of immune repertoires of Chinese and Philippine patients infected with Schistosoma japonicum

T. F. Kresina, X. H. Guan, M. Posner, B. Ramirez, G. R. Olds

Research output: Contribution to journalComment/debate

15 Scopus citations

Abstract

Chinese and Philippine patients exhibited detectable titers of serum antibodies to Schistosoma japonicum worm and egg antigens. Western blot (immunoblot) data revealed differing antigenic profiles. Antigen inhibition studies showed low and high levels of cross-reactivity with anti-worm and anti-egg antibodies, respectively, derived from both Chinese and Philippine patients. Thus, anti-egg antibodies and egg antigens are more conserved than anti-worm antibodies and worm antigens.

Original languageEnglish
Pages (from-to)4698-4700
Number of pages3
JournalInfection and Immunity
Volume59
Issue number12
StatePublished - 1991
Externally publishedYes

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