Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation

Demosthenes G. Katritsis; Demosthenes B. Panagiotakos; Evangelia Karvouni; Eleftherios Giazitzoglou; Socrates Korovesis; George Paxinos; Constantine E. Anagnostopoulos; A. John Camm

doi:10.1016/j.amjcard.2003.07.009

Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation

Demosthenes G. Katritsis
, Demosthenes B. Panagiotakos
, Evangelia Karvouni
, Eleftherios Giazitzoglou
, Socrates Korovesis
, George Paxinos
, Constantine E. Anagnostopoulos
, A. John Camm

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Ninety patients who underwent cardioversion of persistent atrial fibrillation (AF) were randomized to bisoprolol 5 to 10 mg once daily or carvedilol 12.5 to 25 mg twice daily. Using intention-to-treat analysis, 23 patients (46%) in the bisoprolol group and 17 patients (32%) in the carvedilol group relapsed into AF during the 1 year of total follow-up (p = 0.486). Patients treated with carvedilol had a 14% (hazard ratio 0.86) lower risk of relapse of AF compared with patients in the bisoprolol group, although results were statistically insignificant (p = 0.661) after controlling for patient age, gender, baseline heart rate, and left atrial diameter.

Original language	English
Pages (from-to)	1116-1119
Number of pages	4
Journal	American Journal of Cardiology
Volume	92
Issue number	9
DOIs	https://doi.org/10.1016/j.amjcard.2003.07.009
State	Published - 1 Nov 2003
Externally published	Yes

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10.1016/j.amjcard.2003.07.009

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Katritsis, D. G., Panagiotakos, D. B., Karvouni, E., Giazitzoglou, E., Korovesis, S., Paxinos, G., Anagnostopoulos, C. E., & Camm, A. J. (2003). Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation. American Journal of Cardiology, 92(9), 1116-1119. https://doi.org/10.1016/j.amjcard.2003.07.009

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title = "Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation",

abstract = "Ninety patients who underwent cardioversion of persistent atrial fibrillation (AF) were randomized to bisoprolol 5 to 10 mg once daily or carvedilol 12.5 to 25 mg twice daily. Using intention-to-treat analysis, 23 patients (46\%) in the bisoprolol group and 17 patients (32\%) in the carvedilol group relapsed into AF during the 1 year of total follow-up (p = 0.486). Patients treated with carvedilol had a 14\% (hazard ratio 0.86) lower risk of relapse of AF compared with patients in the bisoprolol group, although results were statistically insignificant (p = 0.661) after controlling for patient age, gender, baseline heart rate, and left atrial diameter.",

author = "Katritsis, \{Demosthenes G.\} and Panagiotakos, \{Demosthenes B.\} and Evangelia Karvouni and Eleftherios Giazitzoglou and Socrates Korovesis and George Paxinos and Anagnostopoulos, \{Constantine E.\} and Camm, \{A. John\}",

year = "2003",

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doi = "10.1016/j.amjcard.2003.07.009",

language = "English",

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Katritsis, DG, Panagiotakos, DB, Karvouni, E, Giazitzoglou, E, Korovesis, S, Paxinos, G, Anagnostopoulos, CE & Camm, AJ 2003, 'Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation', American Journal of Cardiology, vol. 92, no. 9, pp. 1116-1119. https://doi.org/10.1016/j.amjcard.2003.07.009

Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation. / Katritsis, Demosthenes G.; Panagiotakos, Demosthenes B.; Karvouni, Evangelia et al.
In: American Journal of Cardiology, Vol. 92, No. 9, 01.11.2003, p. 1116-1119.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation

AU - Katritsis, Demosthenes G.

AU - Panagiotakos, Demosthenes B.

AU - Karvouni, Evangelia

AU - Giazitzoglou, Eleftherios

AU - Korovesis, Socrates

AU - Paxinos, George

AU - Anagnostopoulos, Constantine E.

AU - Camm, A. John

PY - 2003/11/1

Y1 - 2003/11/1

N2 - Ninety patients who underwent cardioversion of persistent atrial fibrillation (AF) were randomized to bisoprolol 5 to 10 mg once daily or carvedilol 12.5 to 25 mg twice daily. Using intention-to-treat analysis, 23 patients (46%) in the bisoprolol group and 17 patients (32%) in the carvedilol group relapsed into AF during the 1 year of total follow-up (p = 0.486). Patients treated with carvedilol had a 14% (hazard ratio 0.86) lower risk of relapse of AF compared with patients in the bisoprolol group, although results were statistically insignificant (p = 0.661) after controlling for patient age, gender, baseline heart rate, and left atrial diameter.

AB - Ninety patients who underwent cardioversion of persistent atrial fibrillation (AF) were randomized to bisoprolol 5 to 10 mg once daily or carvedilol 12.5 to 25 mg twice daily. Using intention-to-treat analysis, 23 patients (46%) in the bisoprolol group and 17 patients (32%) in the carvedilol group relapsed into AF during the 1 year of total follow-up (p = 0.486). Patients treated with carvedilol had a 14% (hazard ratio 0.86) lower risk of relapse of AF compared with patients in the bisoprolol group, although results were statistically insignificant (p = 0.661) after controlling for patient age, gender, baseline heart rate, and left atrial diameter.

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M3 - Article

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SN - 0002-9149

VL - 92

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JO - American Journal of Cardiology

JF - American Journal of Cardiology

IS - 9

ER -

Comparison of effectiveness of carvedilol versus bisoprolol for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation

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