TY - CHAP
T1 - Comparing microarray studies
AU - Suárez-Fariñas, Mayte
AU - Magnasco, Marcelo O.
PY - 2007/3/24
Y1 - 2007/3/24
N2 - We present a practical guide to some of the issues involved in comparing or integrating different microarray studies. We discuss the influence that various factors have on the agreement between studies, such as different technologies and platforms, statistical analysis criteria, protocols, and lab variability. We discuss methods to carry out or refine such comparisons, and detail several, common pitfalls to avoid. Finally, we illustrate these ideas with an example case.
AB - We present a practical guide to some of the issues involved in comparing or integrating different microarray studies. We discuss the influence that various factors have on the agreement between studies, such as different technologies and platforms, statistical analysis criteria, protocols, and lab variability. We discuss methods to carry out or refine such comparisons, and detail several, common pitfalls to avoid. Finally, we illustrate these ideas with an example case.
KW - Crossplatform comparisons
KW - Meta-analysis
KW - Microarray
UR - http://www.scopus.com/inward/record.url?scp=34547665469&partnerID=8YFLogxK
U2 - 10.1385/1-59745-390-0:139
DO - 10.1385/1-59745-390-0:139
M3 - Chapter
C2 - 17634614
AN - SCOPUS:34547665469
SN - 1597453900
SN - 9781597453905
T3 - Methods in Molecular Biology
SP - 139
EP - 152
BT - Microarray Data Analysis
A2 - Korenberg, Michael J.
ER -