Comparative immunological studies of RNA C-type viruses: Radioimmunoassay for a low molecular weight polypeptide of woolly monkey leukemia virus

Steven R. Tronick, John R. Stephenson, Stuart A. Aaronson

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

A 12,000-dalton polypeptide was partially purified from the woolly monkey RNA C-type virus. A sensitive and specific radioimmunoassay for this polypeptide detected major differences in the reactivities of woolly monkey and gibbon ape viruses. In contrast, these viruses were indistinguishable in immunoassays for two other woolly monkey virion proteins, the major structural polypeptide and the reverse transcriptase. Each assay readily differentiated the woolly and gibbon from other mammalian RNA C-type viruses.

Original languageEnglish
Pages (from-to)347-356
Number of pages10
JournalVirology
Volume57
Issue number2
DOIs
StatePublished - Feb 1974
Externally publishedYes

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