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Comparative cranial CT enhancement in the normal primate

  • Burton P. Drayer
  • , Sidney K. Wolfson
  • , Arthur E. Rosenbaum
  • , Manuel Dujovny
  • , Manfred Boehnke
  • , Eugene E. Cook

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/aniibis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal CT enhancement with air was limited by distortion in cerebrospinal fluid spaces. Intrathecal CT enhancement using a low dose of metrizamide accurately delineated the subarachnoid spaces and the brain substance they surrounded with minimal morbidity. Symmetrical brain enhancement (perfusion) was prominent following inhalation CT enhancement; the degree of enhancement correlated with the estimated xenon concentration in the bloodstream. In addition, by performing repeated CT scans during the clearance of xenon from the brain, an approximate analysis of regional cerebral blood flow was obtained.

Original languageEnglish
Pages (from-to)88-96
Number of pages9
JournalInvestigative Radiology
Volume14
Issue number1
DOIs
StatePublished - 1979
Externally publishedYes

Keywords

  • Baboon
  • Cerebral blood flow
  • Computed tomography
  • Cranium
  • Metrizamide
  • Xenon

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