TY - JOUR
T1 - Comorbidity issues in the pharmacological treatment of pathological gambling
T2 - A critical review
AU - Dell'Osso, Bernardo
AU - Allen, Andrea
AU - Hollander, Eric
PY - 2005/10/10
Y1 - 2005/10/10
N2 - Background: Pathological Gambling (PG) is an impulse control disorder often comorbid with other psychopathology, particularly bipolar spectrum disorders, attention deficit/hyperactivity disorder, obsessive-compulsive disorder (OCD) and substance abuse. This paper reviews the published literature on the pharmacological management of PG, highlighting how clinical and subclinical comorbid psychopathology influences the choice of pharmacological treatment. Methods: Using Medline, the authors reviewed relevant articles published on this topic from 1995 to 2005, focusing on the best-designed studies for inclusion. Results: Much of the literature on PG-treatment presupposes different theories regarding this disorder. Data suggest the utility of differentiating the pharmacotherapy of pathological gamblers in light of their comorbid profile, specifically assessing for comorbid bipolar, ADHD, OCD, and substance abuse disorders. Conclusion: Decisions about pharmacological treatment of PG should take into account current and previous comorbid disorders which influence treatment selection.
AB - Background: Pathological Gambling (PG) is an impulse control disorder often comorbid with other psychopathology, particularly bipolar spectrum disorders, attention deficit/hyperactivity disorder, obsessive-compulsive disorder (OCD) and substance abuse. This paper reviews the published literature on the pharmacological management of PG, highlighting how clinical and subclinical comorbid psychopathology influences the choice of pharmacological treatment. Methods: Using Medline, the authors reviewed relevant articles published on this topic from 1995 to 2005, focusing on the best-designed studies for inclusion. Results: Much of the literature on PG-treatment presupposes different theories regarding this disorder. Data suggest the utility of differentiating the pharmacotherapy of pathological gamblers in light of their comorbid profile, specifically assessing for comorbid bipolar, ADHD, OCD, and substance abuse disorders. Conclusion: Decisions about pharmacological treatment of PG should take into account current and previous comorbid disorders which influence treatment selection.
KW - Comorbidity
KW - Compulsive-impulsive spectrum
KW - Impulse control disorders
KW - Pathological gambling
KW - Subthreshold symptoms
UR - http://www.scopus.com/inward/record.url?scp=33744499247&partnerID=8YFLogxK
U2 - 10.1186/1745-0179-1-21
DO - 10.1186/1745-0179-1-21
M3 - Review article
AN - SCOPUS:33744499247
SN - 1745-0179
VL - 1
JO - Clinical Practice and Epidemiology in Mental Health
JF - Clinical Practice and Epidemiology in Mental Health
M1 - 21
ER -