Combined salivary duct carcinoma and squamous cell carcinoma suspected of carcinoma ex pleomorphic adenoma

Tomohiro Enokida, Satoshi Fujii, Hirofumi Kuno, Takashi Mukaigawa, Makoto Tahara, Minoru Sakuraba, Ryuichi Hayashi

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4 Scopus citations

Abstract

A 76-year-old Japanese woman had noticed an asymptomatic and palpable mass in her left parotid gland region for 20 years. The tumor had showed rapid growth during the last two months. Therefore, the tumor was clinically suspected of being a malignant tumor and was surgically resected. A histopathological examination revealed that the tumor consisted of two different histopathological neoplastic components accompanied by hyalinized fibrosis at the center of the tumor. The two-neoplastic components were squamous cell carcinoma and salivary duct carcinoma. The tumor was suspected to be a carcinoma ex pleomorphic adenoma after considering the clinical course and the histopathological findings, such as hyalinized fibrosis at the center of the tumor. There was no evidence of recurrence at 30 months after the surgical resection.

Original languageEnglish
Pages (from-to)460-465
Number of pages6
JournalPathology International
Volume66
Issue number8
DOIs
StatePublished - 1 Aug 2016
Externally publishedYes

Keywords

  • carcinoma ex pleomorphic adenoma
  • mixed salivary gland tumor
  • salivary duct carcinoma
  • salivary gland neoplasm
  • squamous cell carcinoma

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