@article{9488fcd369b44c15bda3df68bd950a5f,
title = "Combined gastric and ileocecal toxicity (serpiginous ulcers) after oral Kayexalate in sorbital therapy",
abstract = "Kayexalate (Roxane Labs, Columbus, OH) in sorbitol is commonly administered by the oral and rectal route for the treatment of hyperkalemia in patients with renal failure. It is believed to have minimal toxicity because it functions as a cation exchanger and is not absorbed. We herein report on a patient who developed identical serpiginous ulcers in the stomach and the terminal ileum after the use of Kayexalate. We believe that this drug could have significant gastrointestinal toxicity in specific patient groups and suggest tentative guidelines, both for the identification of such patients and for the safer use of Kayexalate in these circumstances.",
keywords = "Gastric, Ileocecal, Kayexalate, Ulcers",
author = "Prabir Roy-Chaudhury and Meisels, {Ira S.} and Steven Freedman and Steinman, {Theodore I.} and Michael Steer",
note = "Funding Information: From the Divisions of Nephrology and Gastroenterology, Departments of Medicine and Surgery, Beth Israel Hospital and Harvard Medical School, Boston, MA. Received August 17, 1996; accepted in revised form December 30, 1996. Dr Roy-Chaudhury was the recipient of a National Kidney Foundation Fellowship Award (1994-1996). Address reprint requests to Prabir Roy-Chaudhury, MD, PhD, University of Cincinnati Hospital, Division of Nephrology and Hypertension (MSB 5502) 231 Bethesda Ave, Cincinnati, OH 45267-0557. 0 1997 by the National Kidney Foundation,",
year = "1997",
month = jul,
doi = "10.1016/S0272-6386(97)90574-6",
language = "English",
volume = "30",
pages = "120--122",
journal = "American Journal of Kidney Diseases",
issn = "0272-6386",
publisher = "W.B. Saunders",
number = "1",
}