Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force

S. Gauthier, J. Alam, H. Fillit, T. Iwatsubo, H. Liu-Seifert, M. Sabbagh, S. Salloway, C. Sampaio, J. R. Sims, B. Sperling, R. Sperling, K. A. Welsh-Bohmer, J. Touchon, B. Vellas, P. Aisen

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Combination therapy is expected to play an important role for the treatment of Alzheimer's disease (AD). In October 2018, the European Union-North American Clinical Trials in Alzheimer's Disease Task Force (EU/US CTAD Task Force) met to discuss scientific, regulatory, and logistical challenges to the development of combination therapy for AD and current efforts to address these challenges. Task Force members unanimously agreed that successful treatment of AD will likely require combination therapy approaches that target multiple mechanisms and pathways. They further agreed on the need for global collaboration and sharing of data and resources to accelerate development of such approaches.

Original languageEnglish
Pages (from-to)164-168
Number of pages5
JournalThe journal of prevention of Alzheimer's disease
Issue number3
StatePublished - 2019


  • Alzheimer’s disease
  • amyloid
  • tau
  • therapeutics
  • trial design


Dive into the research topics of 'Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force'. Together they form a unique fingerprint.

Cite this