Colorectal disorders in acquired immune deficiency syndrome

Colorectal disorders are frequent in patients with acquired immune deficiency syndrome (AIDS) and usually manifest by diarrhea, which may be debilitating. Most colorectal disorders are caused by a wide range of bacterial, viral, and protozoan organisms. A systematic approach to the diagnostic evaluation of diarrhea in AIDS begins with stool studies and often includes endoscopic examination with mucosal biopsy. Directed therapy usually results in a better quality of life but, unfortunately, not a prolongation of life.