Colonic perforation in graft versus host disease: A case report

Nandini C. Palaniappa, Laura Doyon, Celia M. Divino

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Graft versus host disease (GVHD) is a phenomenon that occurs after allogeneic bone marrow transplants. Gastrointestinal (GI) manifestations of acute GVHD are common, but severe GI GVHD complications, such as bowel perforation, occur rarely and necessitate surgical intervention. To our knowledge, there are no recorded cases of colonic perforation resulting from GVHD with negative cultures for infectious agents such as cytomegalovirus. We present a case of large bowel perforation due to GVHD.

Original languageEnglish
Pages (from-to)14-16
Number of pages3
JournalInternational Surgery
Issue number1
StatePublished - Jan 2012


  • Autoimmune response
  • Bone marrow transplantation
  • Colonic perforation
  • Graft versus host disease
  • Large bowel


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