Colonic perforation in graft versus host disease: A case report

Nandini C. Palaniappa; Laura Doyon; Celia M. Divino

doi:10.9738/CC76.1

Colonic perforation in graft versus host disease: A case report

Nandini C. Palaniappa, Laura Doyon, Celia M. Divino

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Graft versus host disease (GVHD) is a phenomenon that occurs after allogeneic bone marrow transplants. Gastrointestinal (GI) manifestations of acute GVHD are common, but severe GI GVHD complications, such as bowel perforation, occur rarely and necessitate surgical intervention. To our knowledge, there are no recorded cases of colonic perforation resulting from GVHD with negative cultures for infectious agents such as cytomegalovirus. We present a case of large bowel perforation due to GVHD.

Original language	English
Pages (from-to)	14-16
Number of pages	3
Journal	International Surgery
Volume	97
Issue number	1
DOIs	https://doi.org/10.9738/CC76.1
State	Published - Jan 2012

Keywords

Autoimmune response
Bone marrow transplantation
Colonic perforation
Graft versus host disease
Large bowel

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abstract = "Graft versus host disease (GVHD) is a phenomenon that occurs after allogeneic bone marrow transplants. Gastrointestinal (GI) manifestations of acute GVHD are common, but severe GI GVHD complications, such as bowel perforation, occur rarely and necessitate surgical intervention. To our knowledge, there are no recorded cases of colonic perforation resulting from GVHD with negative cultures for infectious agents such as cytomegalovirus. We present a case of large bowel perforation due to GVHD.",

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AB - Graft versus host disease (GVHD) is a phenomenon that occurs after allogeneic bone marrow transplants. Gastrointestinal (GI) manifestations of acute GVHD are common, but severe GI GVHD complications, such as bowel perforation, occur rarely and necessitate surgical intervention. To our knowledge, there are no recorded cases of colonic perforation resulting from GVHD with negative cultures for infectious agents such as cytomegalovirus. We present a case of large bowel perforation due to GVHD.

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KW - Bone marrow transplantation

KW - Colonic perforation

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KW - Large bowel

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Colonic perforation in graft versus host disease: A case report

Abstract

Keywords

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