Cohesin in determining chromosome architecture

Christian H. Haering; Rolf Jessberger

doi:10.1016/j.yexcr.2012.03.016

Cohesin in determining chromosome architecture

Christian H. Haering
, Rolf Jessberger

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.

Original language	English
Pages (from-to)	1386-1393
Number of pages	8
Journal	Experimental Cell Research
Volume	318
Issue number	12
DOIs	https://doi.org/10.1016/j.yexcr.2012.03.016
State	Published - 15 Jul 2012
Externally published	Yes

Keywords

Chromosome structure
Cohesin
Gene expression
Meiosis
Mitosis
SMC
Sister chromatid cohesion

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10.1016/j.yexcr.2012.03.016

Cite this

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title = "Cohesin in determining chromosome architecture",

abstract = "Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.",

keywords = "Chromosome structure, Cohesin, Gene expression, Meiosis, Mitosis, SMC, Sister chromatid cohesion",

author = "Haering, \{Christian H.\} and Rolf Jessberger",

note = "Funding Information: Work in the authors' laboratories is supported by funding from the German Research Foundation (DFG) Priority Programme 1384 .",

year = "2012",

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doi = "10.1016/j.yexcr.2012.03.016",

language = "English",

volume = "318",

pages = "1386--1393",

journal = "Experimental Cell Research",

issn = "0014-4827",

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T1 - Cohesin in determining chromosome architecture

AU - Haering, Christian H.

AU - Jessberger, Rolf

N1 - Funding Information: Work in the authors' laboratories is supported by funding from the German Research Foundation (DFG) Priority Programme 1384 .

PY - 2012/7/15

Y1 - 2012/7/15

N2 - Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.

AB - Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.

KW - Chromosome structure

KW - Cohesin

KW - Gene expression

KW - Meiosis

KW - Mitosis

KW - SMC

KW - Sister chromatid cohesion

UR - https://www.scopus.com/pages/publications/84861949299

U2 - 10.1016/j.yexcr.2012.03.016

DO - 10.1016/j.yexcr.2012.03.016

M3 - Review article

AN - SCOPUS:84861949299

SN - 0014-4827

VL - 318

SP - 1386

EP - 1393

JO - Experimental Cell Research

JF - Experimental Cell Research

IS - 12

ER -

Cohesin in determining chromosome architecture

Abstract

Keywords

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