TY - JOUR
T1 - Cognitive status changes based on time of day in nursing home patients with and without dementia
AU - Madhusoodanan, Subramoniam
AU - Madhusoodanan, Neha
AU - Serper, Mark
AU - Sullivan, Stephen J.
AU - D'Antonio, Emily
AU - Negi, Rohini
AU - Brenner, Ronald
PY - 2010/9
Y1 - 2010/9
N2 - Background: Changes in behavior and cognition have been observed with disruption of the circadian rhythm. Methods: This study examined the effects of time of day (TOD) on administration of Mini-Mental State Examinations (MMSEs) in nursing home patients with dementia (patients) or functional psychiatric disorders (control), using repeated measures analyses of covariance (ANCOVAs). Results: Controls (n = 34) scored significantly higher than patients (n = 38) on total MMSE and all subscales. Within the patients, men and women performed equally in the morning, but women performed marginally worse in the afternoon on total MMSE scores, orientation, and immediate recall and men performed significantly better in the afternoon. Within the control, no gender or time effects were detected. Conclusion: Results indicate that TOD had no significant impact on cognitive status in patients with dementia or patients with other psychiatric illnesses. No changes in activity timings are recommended in nursing home patients with dementia.
AB - Background: Changes in behavior and cognition have been observed with disruption of the circadian rhythm. Methods: This study examined the effects of time of day (TOD) on administration of Mini-Mental State Examinations (MMSEs) in nursing home patients with dementia (patients) or functional psychiatric disorders (control), using repeated measures analyses of covariance (ANCOVAs). Results: Controls (n = 34) scored significantly higher than patients (n = 38) on total MMSE and all subscales. Within the patients, men and women performed equally in the morning, but women performed marginally worse in the afternoon on total MMSE scores, orientation, and immediate recall and men performed significantly better in the afternoon. Within the control, no gender or time effects were detected. Conclusion: Results indicate that TOD had no significant impact on cognitive status in patients with dementia or patients with other psychiatric illnesses. No changes in activity timings are recommended in nursing home patients with dementia.
KW - changes
KW - cognitive status
KW - nursing home patients
KW - time of day
UR - http://www.scopus.com/inward/record.url?scp=77956471113&partnerID=8YFLogxK
U2 - 10.1177/1533317510372373
DO - 10.1177/1533317510372373
M3 - Article
AN - SCOPUS:77956471113
SN - 1533-3175
VL - 25
SP - 498
EP - 504
JO - American Journal of Alzheimer's Disease and other Dementias
JF - American Journal of Alzheimer's Disease and other Dementias
IS - 6
ER -