TY - JOUR
T1 - Code-ICH
T2 - A New Paradigm for Emergency Intervention
AU - Yakhkind, Aleksandra
AU - Yu, Wenzheng
AU - Li, Qi
AU - Goldstein, Joshua N.
AU - Mayer, Stephan A.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
PY - 2024/9
Y1 - 2024/9
N2 - Purpose of review: Intracerebral hemorrhage (ICH) is the most devastating type of stroke, causing widespread disability and mortality. Unfortunately, the acute care of ICH has lagged behind that of ischemic stroke. There is an increasing body of evidence supporting the importance of early interventions including aggressive control of blood pressure and reversal of anticoagulation in the initial minutes to hours of presentation. This review highlights scientific evidence behind a new paradigm to care for these patients called Code-ICH. Recent findings: While numerous trials aimed at decreasing hematoma expansion through single interventions had failed to show statistically significant effects on primary outcomes, time-sensitive, multifaceted, bundled care approaches have recently shown substantial promise in improving functional outcomes in patients with ICH. Summary: The concept of Code-ICH can serve as a structural platform for the practice of acute care neurology to continuously measure its performance, reflect on best practices, advance care, and address disparities.
AB - Purpose of review: Intracerebral hemorrhage (ICH) is the most devastating type of stroke, causing widespread disability and mortality. Unfortunately, the acute care of ICH has lagged behind that of ischemic stroke. There is an increasing body of evidence supporting the importance of early interventions including aggressive control of blood pressure and reversal of anticoagulation in the initial minutes to hours of presentation. This review highlights scientific evidence behind a new paradigm to care for these patients called Code-ICH. Recent findings: While numerous trials aimed at decreasing hematoma expansion through single interventions had failed to show statistically significant effects on primary outcomes, time-sensitive, multifaceted, bundled care approaches have recently shown substantial promise in improving functional outcomes in patients with ICH. Summary: The concept of Code-ICH can serve as a structural platform for the practice of acute care neurology to continuously measure its performance, reflect on best practices, advance care, and address disparities.
KW - Bundled Care
KW - Clinical Protocols
KW - Hematoma Expansion
KW - Hemostasis Control
KW - Intracerebral Hemorrhage
KW - Neurologic Emergency
UR - http://www.scopus.com/inward/record.url?scp=85200161032&partnerID=8YFLogxK
U2 - 10.1007/s11910-024-01364-9
DO - 10.1007/s11910-024-01364-9
M3 - Review article
AN - SCOPUS:85200161032
SN - 1528-4042
VL - 24
SP - 365
EP - 371
JO - Current Neurology and Neuroscience Reports
JF - Current Neurology and Neuroscience Reports
IS - 9
ER -