Cluster analysis of the origins of the new influenza A(H1N1) virus.

A. Solovyov; G. Palacios; T. Briese; W. I. Lipkin; R. Rabadan

doi:10.2807/ese.14.21.19224-en

Cluster analysis of the origins of the new influenza A(H1N1) virus.

A. Solovyov, G. Palacios, T. Briese, W. I. Lipkin, R. Rabadan

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

In March and April 2009, a new strain of influenza A(H1N1) virus has been isolated in Mexico and the United States. Since the initial reports more than 10,000 cases have been reported to the World Health Organization, all around the world. Several hundred isolates have already been sequenced and deposited in public databases. We have studied the genetics of the new strain and identified its closest relatives through a cluster analysis approach. We show that the new virus combines genetic information related to different swine influenza viruses. Segments PB2, PB1, PA, HA, NP and NS are related to swine H1N2 and H3N2 influenza viruses isolated in North America. Segments NA and M are related to swine influenza viruses isolated in Eurasia.

Original language	English
Journal	Eurosurveillance
Volume	14
Issue number	21
DOIs	https://doi.org/10.2807/ese.14.21.19224-en
State	Published - 2009
Externally published	Yes

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title = "Cluster analysis of the origins of the new influenza A(H1N1) virus.",

abstract = "In March and April 2009, a new strain of influenza A(H1N1) virus has been isolated in Mexico and the United States. Since the initial reports more than 10,000 cases have been reported to the World Health Organization, all around the world. Several hundred isolates have already been sequenced and deposited in public databases. We have studied the genetics of the new strain and identified its closest relatives through a cluster analysis approach. We show that the new virus combines genetic information related to different swine influenza viruses. Segments PB2, PB1, PA, HA, NP and NS are related to swine H1N2 and H3N2 influenza viruses isolated in North America. Segments NA and M are related to swine influenza viruses isolated in Eurasia.",

author = "A. Solovyov and G. Palacios and T. Briese and Lipkin, \{W. I.\} and R. Rabadan",

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AU - Solovyov, A.

AU - Palacios, G.

AU - Briese, T.

AU - Lipkin, W. I.

AU - Rabadan, R.

PY - 2009

Y1 - 2009

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AB - In March and April 2009, a new strain of influenza A(H1N1) virus has been isolated in Mexico and the United States. Since the initial reports more than 10,000 cases have been reported to the World Health Organization, all around the world. Several hundred isolates have already been sequenced and deposited in public databases. We have studied the genetics of the new strain and identified its closest relatives through a cluster analysis approach. We show that the new virus combines genetic information related to different swine influenza viruses. Segments PB2, PB1, PA, HA, NP and NS are related to swine H1N2 and H3N2 influenza viruses isolated in North America. Segments NA and M are related to swine influenza viruses isolated in Eurasia.

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SN - 1560-7917

VL - 14

JO - Eurosurveillance

JF - Eurosurveillance

IS - 21

ER -

Cluster analysis of the origins of the new influenza A(H1N1) virus.

Abstract

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