Clinically Actionable Strategies for Studying Neural Influences in Cancer

Ihsan Ekin Demir; Carmen Mota Reyes; Wasfi Alrawashdeh; Güralp O. Ceyhan; Sylvie Deborde; Helmut Friess; Kivanc Görgülü; Rouzanna Istvanffy; David Jungwirth; Rohini Kuner; Maria Maryanovich; Shorook Na'ara; Simon Renders; Jami L. Saloman; Nicole N. Scheff; Hendrik Steenfadt; Pavel Stupakov; Vera Thiel; Divij Verma; Bengi Su Yilmaz; Ruth A. White; Timothy C. Wang; Richard J. Wong; Paul S. Frenette; Ziv Gil; Brian M. Davis

doi:10.1016/j.ccell.2020.05.023

Clinically Actionable Strategies for Studying Neural Influences in Cancer

Ihsan Ekin Demir, Carmen Mota Reyes, Wasfi Alrawashdeh, Güralp O. Ceyhan, Sylvie Deborde, Helmut Friess, Kivanc Görgülü, Rouzanna Istvanffy, David Jungwirth, Rohini Kuner, Maria Maryanovich, Shorook Na'ara, Simon Renders, Jami L. Saloman, Nicole N. Scheff, Hendrik Steenfadt, Pavel Stupakov, Vera Thiel, Divij Verma, Bengi Su YilmazRuth A. White, Timothy C. Wang, Richard J. Wong, Paul S. Frenette, Ziv Gil, Brian M. Davis

Research output: Contribution to journal › Comment/debate

19 Scopus citations

Abstract

Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.

Original language	English
Pages (from-to)	11-14
Number of pages	4
Journal	Cancer Cell
Volume	38
Issue number	1
DOIs	https://doi.org/10.1016/j.ccell.2020.05.023
State	Published - 13 Jul 2020
Externally published	Yes

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Demir, I. E., Reyes, C. M., Alrawashdeh, W., Ceyhan, G. O., Deborde, S., Friess, H., Görgülü, K., Istvanffy, R., Jungwirth, D., Kuner, R., Maryanovich, M., Na'ara, S., Renders, S., Saloman, J. L., Scheff, N. N., Steenfadt, H., Stupakov, P., Thiel, V., Verma, D., ... Davis, B. M. (2020). Clinically Actionable Strategies for Studying Neural Influences in Cancer. Cancer Cell, 38(1), 11-14. https://doi.org/10.1016/j.ccell.2020.05.023

@article{a87a7212151f450e9197d6aa3f7efac4,

title = "Clinically Actionable Strategies for Studying Neural Influences in Cancer",

abstract = "Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.",

author = "Demir, {Ihsan Ekin} and Reyes, {Carmen Mota} and Wasfi Alrawashdeh and Ceyhan, {G{\"u}ralp O.} and Sylvie Deborde and Helmut Friess and Kivanc G{\"o}rg{\"u}l{\"u} and Rouzanna Istvanffy and David Jungwirth and Rohini Kuner and Maria Maryanovich and Shorook Na'ara and Simon Renders and Saloman, {Jami L.} and Scheff, {Nicole N.} and Hendrik Steenfadt and Pavel Stupakov and Vera Thiel and Divij Verma and Yilmaz, {Bengi Su} and White, {Ruth A.} and Wang, {Timothy C.} and Wong, {Richard J.} and Frenette, {Paul S.} and Ziv Gil and Davis, {Brian M.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = jul,

day = "13",

doi = "10.1016/j.ccell.2020.05.023",

language = "English",

volume = "38",

pages = "11--14",

journal = "Cancer Cell",

issn = "1535-6108",

publisher = "Cell Press",

number = "1",

}

Demir, IE, Reyes, CM, Alrawashdeh, W, Ceyhan, GO, Deborde, S, Friess, H, Görgülü, K, Istvanffy, R, Jungwirth, D, Kuner, R, Maryanovich, M, Na'ara, S, Renders, S, Saloman, JL, Scheff, NN, Steenfadt, H, Stupakov, P, Thiel, V, Verma, D, Yilmaz, BS, White, RA, Wang, TC, Wong, RJ, Frenette, PS, Gil, Z & Davis, BM 2020, 'Clinically Actionable Strategies for Studying Neural Influences in Cancer', Cancer Cell, vol. 38, no. 1, pp. 11-14. https://doi.org/10.1016/j.ccell.2020.05.023

TY - JOUR

T1 - Clinically Actionable Strategies for Studying Neural Influences in Cancer

AU - Demir, Ihsan Ekin

AU - Reyes, Carmen Mota

AU - Alrawashdeh, Wasfi

AU - Ceyhan, Güralp O.

AU - Deborde, Sylvie

AU - Friess, Helmut

AU - Görgülü, Kivanc

AU - Istvanffy, Rouzanna

AU - Jungwirth, David

AU - Kuner, Rohini

AU - Maryanovich, Maria

AU - Na'ara, Shorook

AU - Renders, Simon

AU - Saloman, Jami L.

AU - Scheff, Nicole N.

AU - Steenfadt, Hendrik

AU - Stupakov, Pavel

AU - Thiel, Vera

AU - Verma, Divij

AU - Yilmaz, Bengi Su

AU - White, Ruth A.

AU - Wang, Timothy C.

AU - Wong, Richard J.

AU - Frenette, Paul S.

AU - Gil, Ziv

AU - Davis, Brian M.

PY - 2020/7/13

Y1 - 2020/7/13

N2 - Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.

AB - Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.

UR - http://www.scopus.com/inward/record.url?scp=85087484678&partnerID=8YFLogxK

U2 - 10.1016/j.ccell.2020.05.023

DO - 10.1016/j.ccell.2020.05.023

M3 - Comment/debate

C2 - 32531270

AN - SCOPUS:85087484678

SN - 1535-6108

VL - 38

SP - 11

EP - 14

JO - Cancer Cell

JF - Cancer Cell

IS - 1

ER -

Clinically Actionable Strategies for Studying Neural Influences in Cancer

Abstract

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