Clinical trial of etoposide and cisplatin as salvage therapy in advanced ovarian carcinoma

Peter R. Dottino, Howard M. Goodman, Daniel Kredentser, Marilyn Rosenberg, Carmel J. Cohen

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The combination of etoposide and cis-platinum was evaluated in the treatment of advanced ovarian cancer. Of 13 treated patients, 4 demonstrated complete clinical responses and 3 demonstrated partial clinical responses. The mean progression free interval was 14+ months for the complete responders and 8.3+ months for the partial responders. The 100 mg/m2 dose of etoposide appears to be critical in attaining response. This etoposide and cis-platinum combination appears to be effective as a salvage regimen in ovarian carcicnoma.

Original languageEnglish
Pages (from-to)350-356
Number of pages7
JournalGynecologic Oncology
Volume27
Issue number3
DOIs
StatePublished - Jul 1987

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