Clinical study on inpatients with chronic kidney disease and hypertension

Objective: To investigate the clinical characteristics of inpatients with chronic kidney disease (CKD) and hypertension. Methods: A cross-sectional and retrospective epidemiological study was carried out. The rates of incidence, awareness, treatment, and control of hypertension of inpatients with CKD admitted by the Department of Nephrology of Renji Hospital, Shanghai Jiao Tong University School of Medicine from November 2009 to February 2010 were surveyed and risk factors and the use of antihypertensive drugs were investigated. The control of hypertension and adverse events of patients with CKD and hypertension was surveyed by telephone from June to August 2015. Results: A total of 439 patients with CKD were enrolled. The rates of incidence, awareness, treatment, and control of hypertension were 69.5% (305/439), 95.4% (291/305), 92.8% (283/305), and 36.4% (111/305), respectively. 61.3% (187/305) of inpatients with CKD and hypertension were administrated with more than one antihypertensive drug. Follow-up after 5 years revealed that the rate of adverse events of patients with poor control of hypertension was significantly higher than that of patients with well control of hypertension (P<0.001). Conclusion: (1)The rates of incidence, awareness, and treatment of hypertension of patients with CKD are high, while the rate of well control of hypertension is low. (2)Most patients with CKD use more than one antihypertensive drug to control the blood pressure. (3)Well control of hypertension can remarkably reduce the incidence of adverse events.