Clinical study of coil embolization for intracranial wide-necked aneurysms

Objective: To analyze the efficacy of endovascular coil embolization for intracranial wide-necked aneurysms and follow-up results. Methods: Fifty-eight patients with wide-necked aneurysms were treated with multiple endovascular strategies. 46 intracranial wide-necked aneurysms (45 patients) were treated with stent-assisted coil embolization, 13 (12 patients) with balloon-assisted embolization, and 1 with double microcatheter technique embolization. Immediate postprocedure and follow-up results were evaluated. The main outcome was measured with modified Rankin scale. DSA or MRA were used for imaging follow-up. Results: Grade 0 aneurysm occlusion was achieved in 14 aneurysms, Grade 1 in 29 aneurysms, Grade 2 in 15 aneurysms, Grade 3 in 2 aneurysms. 5 suffered procedure-related thromboembolic events. After a mean follow-up of 13.9 months, modified Rankin Scale was 0 in 42 cases, 1 in 8 cases, 2 in 3 cases, 3 in 2 cases, 4 in 2 cases and 5 in 1 case. 2 aneurysms were retreated because of recurrence. Conclusion: Endovascular embolization can be performed safely and effectively in intracranial wide-necked aneurysms. Thromboembolic events are the main compications during or after procedure, with inadequate antiplatelet the main reason.