Clinical review 130: Addison's disease 2001

Svetlana Ten, Maria New, Noel Maclaren

Research output: Contribution to journalReview articlepeer-review

341 Scopus citations


Whereas it is now more than 150 yr since T. Addison first described the clinical and pathological features of adrenal failure (1), the disease remains underdiagnosed, leading to unnecessary morbidity and mortality. Over the past decade, there have been important advances in elucidating the pathogeneses and underlying genetics of the individual forms of the disease. This review emphasizes the multiple etiologies and the diagnostic steps to be taken with consideration to age at onset and gender and summarizes new genetic insights in the disease.

Original languageEnglish
Pages (from-to)2909-2922
Number of pages14
JournalJournal of Clinical Endocrinology and Metabolism
Issue number7
StatePublished - 2001
Externally publishedYes


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