Clinical performance of roche Cobas 4800 HPV test

Miao Cui; Nicholas Chan; Momo Liu; Khanh Thai; Joanna Malaczynska; Ila Singh; David Zhang; Fei Ye

doi:10.1128/JCM.00883-14

Clinical performance of roche Cobas 4800 HPV test

Miao Cui
, Nicholas Chan
, Momo Liu
, Khanh Thai
, Joanna Malaczynska
, Ila Singh
, David Zhang
, Fei Ye

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Evaluation of the Cobas 4800 test demonstrated that Cobas had a low rate of cross-reactivity with low-risk human papillomavirus (lrHPV), a 3.74% disconcordance rate between prealiquots and postaliquots, and failure rates of 4.57% and 1.16%, respectively, after vortexing and swirling. This study demonstrated that the Cobas test has good sensitivity, accuracy, and reproducibility for detecting 14 high-risk HPV (hrHPV) genotypes.

Original language	English
Pages (from-to)	2210-2211
Number of pages	2
Journal	Journal of Clinical Microbiology
Volume	52
Issue number	6
DOIs	https://doi.org/10.1128/JCM.00883-14
State	Published - Jun 2014

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title = "Clinical performance of roche Cobas 4800 HPV test",

abstract = "Evaluation of the Cobas 4800 test demonstrated that Cobas had a low rate of cross-reactivity with low-risk human papillomavirus (lrHPV), a 3.74\% disconcordance rate between prealiquots and postaliquots, and failure rates of 4.57\% and 1.16\%, respectively, after vortexing and swirling. This study demonstrated that the Cobas test has good sensitivity, accuracy, and reproducibility for detecting 14 high-risk HPV (hrHPV) genotypes.",

author = "Miao Cui and Nicholas Chan and Momo Liu and Khanh Thai and Joanna Malaczynska and Ila Singh and David Zhang and Fei Ye",

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AU - Cui, Miao

AU - Chan, Nicholas

AU - Liu, Momo

AU - Thai, Khanh

AU - Malaczynska, Joanna

AU - Singh, Ila

AU - Zhang, David

AU - Ye, Fei

PY - 2014/6

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AB - Evaluation of the Cobas 4800 test demonstrated that Cobas had a low rate of cross-reactivity with low-risk human papillomavirus (lrHPV), a 3.74% disconcordance rate between prealiquots and postaliquots, and failure rates of 4.57% and 1.16%, respectively, after vortexing and swirling. This study demonstrated that the Cobas test has good sensitivity, accuracy, and reproducibility for detecting 14 high-risk HPV (hrHPV) genotypes.

UR - https://www.scopus.com/pages/publications/84901660830

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DO - 10.1128/JCM.00883-14

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ER -

Clinical performance of roche Cobas 4800 HPV test

Abstract

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