Clinical outcomes following heart transplantation

Laura Murphy, Sean P. Pinney

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Since its first performance in 1967, cardiac transplantation has emerged from a medical curiosity to become the treatment of choice for advanced heart failure. Refinements in surgical technique, development of a standardized endomyocardial biopsy grading system, and the discovery of newer immunosuppressive medications have improved the outlook for today's heart-transplant recipients. For the most recent era, median survival has increased to 10 years and median survival conditional upon surviving the first transplant year is now >14 years. Quality oflife is excellent. This article will concisely review the major clinical outcomes following transplantation including survival, quality of life, immunosuppression, and short- and long-term complications.

Original languageEnglish
Pages (from-to)317-329
Number of pages13
JournalMount Sinai Journal of Medicine
Issue number3
StatePublished - May 2012


  • Calcineurin inhibitors
  • Cardiac allograft vasculopathy
  • Endomyocardial biopsy
  • Heart transplant


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