Clinical Outcomes After Heterogeneous Overlap Stenting With Drug-Eluting Stents and Bare-Metal Stents for de Novo Coronary Artery Narrowings

Jiro Aoki, Ajay J. Kirtane, George D. Dangas, Alexandra J. Lansky, Andy Morales, Masashi Kimura, Young Hak Kim, Issam Moussa, Giora Weisz, Edward M. Kreps, Michael Collins, Theresa Frankin-Bond, Gregg W. Stone, Jeffrey W. Moses, Martin B. Leon, Roxana Mehran

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

When it is difficult to deliver multiple drug-eluting stents (DES) or when size constraints limit DES implantation, bare-metal stents (BMS) may be implanted contiguous to DES. However, the clinical outcomes after overlapping DES and BMS implantation are not known. From September 2004 to June 2006, 4,872 consecutive patients who underwent percutaneous coronary intervention consented to be enrolled in a prospective registry. Of these patients, 44 (0.9%) with de novo lesions were treated with DES and BMS overlap stenting. All patients were followed to 12 months for the assessment of clinical outcomes. The average implanted stent diameter was 2.68 ± 0.30 mm for DES and 2.35 ± 0.38 mm for BMS. Overlapping BMS were implanted distal to DES in all but 1 case. One patient (2.3%) experienced acute stent thrombosis and died 2 days after the procedure. No other patient died or had a myocardial infarction during 12 months. The target vessel revascularization rate at 12 months, however, was 31.8%, mainly driven by diffuse in-stent restenosis in the BMS segments. In conclusion, the incidence of DES and BMS overlap stenting is rare in daily practice, but this procedure is associated with a high rate of target vessel revascularization.

Original languageEnglish
Pages (from-to)58-62
Number of pages5
JournalAmerican Journal of Cardiology
Volume101
Issue number1
DOIs
StatePublished - 1 Jan 2008
Externally publishedYes

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