Clinical Implications of Dystonia as a Neural Network Disorder

Giovanni Battistella; Kristina Simonyan

doi:10.1007/978-3-031-26220-3_13

Clinical Implications of Dystonia as a Neural Network Disorder

Giovanni Battistella
, Kristina Simonyan

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

13 Scopus citations

Abstract

Isolated dystonia is a neurological disorder of diverse etiology, multifactorial pathophysiology, and wide spectrum of clinical presentations. We review the recent neuroimaging advances that led to the conceptualization of dystonia as a neural network disorder and discuss how current knowledge is shaping the identification of biomarkers of dystonia and the development of novel pharmacological therapies.

Original language	English
Title of host publication	Advances in Neurobiology
Publisher	Springer
Pages	223-240
Number of pages	18
DOIs	https://doi.org/10.1007/978-3-031-26220-3_13
State	Published - 2023
Externally published	Yes

Publication series

Name	Advances in Neurobiology
Volume	31
ISSN (Print)	2190-5215
ISSN (Electronic)	2190-5223

Keywords

Connectome
Functional connectivity
Network disorder
Neurotransmission
Structural networks

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10.1007/978-3-031-26220-3_13

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title = "Clinical Implications of Dystonia as a Neural Network Disorder",

abstract = "Isolated dystonia is a neurological disorder of diverse etiology, multifactorial pathophysiology, and wide spectrum of clinical presentations. We review the recent neuroimaging advances that led to the conceptualization of dystonia as a neural network disorder and discuss how current knowledge is shaping the identification of biomarkers of dystonia and the development of novel pharmacological therapies.",

keywords = "Connectome, Functional connectivity, Network disorder, Neurotransmission, Structural networks",

author = "Giovanni Battistella and Kristina Simonyan",

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AU - Simonyan, Kristina

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AB - Isolated dystonia is a neurological disorder of diverse etiology, multifactorial pathophysiology, and wide spectrum of clinical presentations. We review the recent neuroimaging advances that led to the conceptualization of dystonia as a neural network disorder and discuss how current knowledge is shaping the identification of biomarkers of dystonia and the development of novel pharmacological therapies.

KW - Connectome

KW - Functional connectivity

KW - Network disorder

KW - Neurotransmission

KW - Structural networks

UR - https://www.scopus.com/pages/publications/85163658649

U2 - 10.1007/978-3-031-26220-3_13

DO - 10.1007/978-3-031-26220-3_13

M3 - Chapter

C2 - 37338705

AN - SCOPUS:85163658649

T3 - Advances in Neurobiology

SP - 223

EP - 240

BT - Advances in Neurobiology

PB - Springer

ER -

Clinical Implications of Dystonia as a Neural Network Disorder

Abstract

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Keywords

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