The study of atherosclerotic disease during its natural history and after therapeutic intervention will enhance our understanding of disease progression and regression and aid in selecting appropriate treatments. Several invasive and noninvasive imaging techniques are available to assess atherosclerotic vessels. Most of the standard techniques identify luminal diameter, stenosis, wall thickness, and plaque volume; however, none can characterize plaque composition and therefore identify the high-risk plaques. We will present the different imaging modalities that have been used for the direct assessment of the carotid, aortic, and coronary atherosclerotic plaques. We will review in detail the use of high-resolution, multicontrast magnetic resonance for the noninvasive imaging of vulnerable plaques and the characterization of plaques in terms of their various components (ie, lipid, fibrous, calcium, or thrombus).

Original languageEnglish
Pages (from-to)305-316
Number of pages12
JournalCirculation Research
Issue number4
StatePublished - 17 Aug 2001


  • Atherosclerosis
  • Computed tomography
  • Lipid-lowering
  • Magnetic resonance imaging
  • Ultrasound


Dive into the research topics of 'Clinical imaging of the high-risk or vulnerable atherosclerotic plaque'. Together they form a unique fingerprint.

Cite this